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Vitamin D assessment (ViDA) study

Research Project

originally posted by Research Admin on 2013-12-20 13:21:39.996 and updated 2018-08-08 11:04:47.478

Description

ViDA is a large research study involving more than 5,000 people from Auckland aged 50-84 years. It was a four-year study, and one of the largest studies of vitamin D ever undertaken.

ViDA began enrolling participants in May 2011 and completed enrolment in December 2012. ViDA is now completed, and final results are being published.

ViDA participants were closely followed up over 4 years to see if taking vitamin D supplements reduces the risk of:

  • Cardiovascular disease (eg, heart attacks, strokes, or blood vessel diseases which may cause poor circulation and high blood pressure)
  • Respiratory infections (eg, pneumonia, bronchitis)
  • Falls and fractures

The study is particularly interested in rates of hospitalization for these medical conditions. Within the main study, they are also following the progress of a small group of people who have psoriasis, a common skin disorder possibly linked to vitamin D. Another small group is having bone density scans done to assess bone strength and find out how vitamin D is connected to this.

Start Date

2011-05-01

Status

In Progress

Location

Auckland

Dissemination

https://www.fmhs.auckland.ac.nz/en/soph/about/our-departments/epidemiology-and-biostatistics/research/vida-study.html

Researchers

Robert Scragg
Carlos A. Camargo
Alistair W. Stewart
Carlene M. M. Lawes
Les Toop
Kay-Tee Khaw

Research Abstracts

Monthly vitamin D supplementation, pain, and pattern of analgesic prescription: Secondary analysis from the randomized, double-blind, placebo-controlled ViDA study

Effects of vitamin D supplementation on adherence to and persistence with long-term statin therapy: Secondary analysis from the randomized, double-blind, placebo-controlled ViDA study

Monthly high-dose vitamin D3 supplementation and self-reported adverse events in a 4-year randomized controlled trial

Monthly high-dose vitamin D supplementation and cancer risk: A post hoc analysis of the vitamin D assessment randomized clinical trial

Effect of monthly high-dose vitamin D supplementation on falls and non-vertebral fractures: Secondary and post-hoc outcomes from the randomised, double-blind, placebo-controlled ViDA trial

Limitations of vitamin D supplementation trials: Why observational studies will continue to help determine the role of vitamin D in health

A randomized, double-blind, placebo-controlled trial of the effect of monthly vitamin D supplementation in mild psoriasis

Effect of monthly high-dose vitamin D supplementation on cardiovascular disease in the Vitamin D Assessment Study: A randomized clinical trial

Effect of monthly, high‐dose, long‐term vitamin D supplementation on central blood pressure parameters: A randomized controlled trial substudy

The association between vitamin D concentration and pain: A systematic review and meta-analysis

Effect of monthly, high-dose, long-term vitamin D on lung function: A randomized controlled trial

25‐Hydroxyvitamin D threshold for the effects of vitamin D supplements on bone density secondary analysis of a randomized controlled trial

The Vitamin D Assessment (ViDA) Study: Design of a randomized controlled trial of vitamin D supplementation for the prevention of cardiovascular disease, acute respiratory infection, falls and non-vertebral fractures

Effect of monthly high-dose vitamin D on bone density in community-dwelling older adults sub-study of a randomized controlled trial

Oral vitamin D3 supplementation for chronic plaque psoriasis: A randomized, double-blind, placebo-controlled trial