Predicted lean body mass, fat mass, and all cause and cause specific mortality in men: Prospective US cohort study
posted by WM Admin on 2018-07-04 16:46:23.342
The authors investigated the association of predicted lean body mass, fat mass, and body mass index (BMI) with all cause and cause specific mortality in men.
Participants were 38 006 men (aged 40-75 years) from the Health Professionals Follow-up Study, followed up for death (1987-2012).
The authors found a strong positive association between predicted fat mass and mortality and a U shaped association between predicted lean body mass and mortality in men. They suggest that low lean body mass, rather than low fat mass, may be driving the increased risk of mortality in the lower BMI range. Understanding the independent roles of lean body mass and fat mass has important implications for clarifying the obesity paradox phenomenon in the association between BMI and mortality.
This is an open access article and can be read in free full text at: https://doi.org/10.1136/bmj.k2575
Lee, D.H., et al. (2018). Predicted lean body mass, fat mass, and all cause and cause specific mortality in men: prospective US cohort study. BMJ, 362:k2575.