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Metabolic syndrome in pregnancy and risk for adverse pregnancy outcomes: A prospective cohort of nulliparous women

NZ Research Abstract

posted by Research Admin on 6 December 2018


Jessica A. Grieger
Tina Bianco-Miotto
Luke E Grzeskowiak
Shalem Y. Leemaqz
Lucilla Poston
Lesley M. E. McCowan
Louise C. Kenny
Jenny Myers
James J. Walker
Gustaaf A. Dekker
Claire T. Roberts

Year of Publication



PLoS Med 15(12): e1002710

Publication Type

Journal article (peer reviewed)

Publication Status



In this study, the authors sought to examine the impact of maternal metabolic syndrome (MetS) on pregnancy outcomes. They assessed the links between MetS, measured at 15 ± 1 weeks’ gestation, and a range of pregnancy complications in low-risk, nulliparous women recruited to the multi-centre, international prospective Screening for Pregnancy Endpoints (SCOPE) study. The authors found that more than half of the women who had MetS in early pregnancy developed a pregnancy complication compared with just over a third of women who did not have MetS, and that "while increasing BMI increases the probability of gestational diabetes GDM [gestational diabetes mellitus], the addition of MetS exacerbates this probability".

Type of Study


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