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Investigations of the Mechanisms of Diabetes Remission: A Focus on Adaptive Thermogenesis

NZ Research Abstract

posted by Research Admin 1 on 12 February 2019


Brian T. Corley

Year of Publication



(Thesis, Doctor of Philosophy) University of Otago.

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Publication Status



This thesis proves the hypothesis that a low-calorie diet combined with intermittent fasting can reduce the negative energy balance associated with weight loss is false. "This is partly due to a compensatory reduction in resting energy expenditure (REE), adaptive thermogenesis, that occurs during weight loss... Of note, intermittent fasting was associated with a two-fold greater reduction in fat mass compared to continuous daily restriction."

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